منابع مشابه
Re: hydroxyproline metabolism in mouse models of primary hyperoxaluria.
Primary hyperoxaluria type 1 (PH1) and type 2 (PH2) are rare genetic diseases that result from deficiencies in glyoxylate metabolism. The increased oxalate synthesis that occurs can lead to kidney stone formation, deposition of calcium oxalate in the kidney and other tissues, and renal failure. Hydroxyproline (Hyp) catabolism, which occurs mainly in the liver and kidney, is a prominent source o...
متن کاملHydroxyproline metabolism in mouse models of primary hyperoxaluria
John Knight, Ross P. Holmes, Scott D. Cramer, Tatsuya Takayama, and Eduardo Salido Departments of Urology and Cancer Biology, Wake Forest University Health Sciences, Winston-Salem, North Carolina; Department of Pharmacology, University of Colorado, Denver, Anschutz Medical Campus, Aurora, Colorado; and Center for Biomedical Research on Rare Diseases, Hospital Universitario Canarias, Instituto T...
متن کاملContiguous hydroxyproline residues direct hydroxyproline arabinosylation in Nicotiana tabacum.
Hydroxyproline (Hyp) O-glycosylation characterizes the hydroxyproline-rich glycoprotein (HRGP) superfamily of the plant extracellular matrix. Hyp glycosylation occurs in two modes: Arabinosylation adds short oligoarabinosides (Hyp-arabinosides) while galactosylation leads to the addition of larger arabinogalactan polysaccharides (Hyp-polysaccharides). We hypothesize that sequence-dependent glyc...
متن کاملMetabolism of glycine- and hydroxyproline-containing peptides by the isolated perfused rat kidney.
Isolated perfused rat kidneys removed considerable quantities of glycyltyrosine, glycylhydroxyproline, tetraglycine and prolylhydroxyproline from the perfusate. The component amino acids are released into the perfusate and, in the case of the glycine-containing peptides, there is increased synthesis of serine. Removal of peptides was more than could be accounted for on the basis of filtration, ...
متن کاملDistribution and metabolism of protein-bound hydroxyproline in an elongating tissue, the Avena coleoptile.
A study has been made of the distribution and metabolism of protein-bound hydroxyproline in an elongating tissue, the excised Avena coleoptile. The hydroxyproline-containing proteins of this tissue have been separated into 3 fractions on the basis of their solubilities. The cytoplasmic, trichloroacetic acid-insoluble proteins (S-fraction) contain the bulk of the proline of the cells but only 20...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1960
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)64497-7